Publications

2022

• Gell: A GPU-powered 3D hybrid simulator for large-scale multicellular system Jiayi Du, Yu Zhou, Lihua Jin,  Ke Sheng, https://www.biorxiv.org/content/10.1101/2022.09.01.506296v1 doi.org/10.1101/2022.09.01.506296

• Magnetic resonance imaging-guided versus computed tomography-guided stereotactic body radiotherapy for prostate cancer (MIRAGE): Primary Endpoint Analysis of a Phase III Randomized Trial Amar U. Kishan Ting Martin Ma, James M. Lamb, Maria Casado, Holly Wilhalme, Daniel A. Low, Ke Sheng, Sahil Sharma, Yingli Yang, Yu Gao, John Neylon, Vincent Basehart, Minsong Cao, Michael L. Steinberg JAMA Oncol. 2023 Jan 12. doi: 10.1001/jamaoncol.2022.6558

• Tomographic detection of photon pairs produced from high-energy X-rays for the monitoring of radiotherapy dosing, Qihui Lyu, Ryan Neph, Ke Sheng, Nature BME, 2022 https://www.nature.com/articles/s41551-022-00953-8

• Dose and dose rate objectives in Bragg peak and shoot-through beam orientation optimization for FLASH proton therapy, Pavitra Ramesh, Wenbo Gu, Dan Ruan, Ke Sheng, Medical Physics, Med Phys. 2022 Oct 12. doi: 10.1002/mp.1600

• An efficient rectangular optimization method for sparse orthogonal collimator based small animal irradiation Lu Jiang, Qihui Lyu, Amr M H Abdelhamid, Susanta Hui, Ke Sheng, Physics and Medicine in Biology,  2022, doi:10.1088/1361-6560/ac910b

• Evaluation of T2-Weighted MRI for Visualization and Sparing of Urethra with MR-Guided Radiation Therapy (MRgRT) On-Board MRI. Pham J, Savjani RR, Gao Y, Cao M, Hu P, Sheng K, Low DA, Steinberg M, Kishan AU, Yang Y. Cancers (Basel). 2021 Jul 16;13(14):3564. doi: 10.3390/cancers13143564.

• Fully Automated Segmentation of Prostatic Urethra for MR-Guided Radiation Therapy (MRgRT), Di Xu, Ting Martin Ma, Ricky Savjani, Jonathan Pham, Minsong Cao, Yingli Yang, Amar U. Kishan, Fabien Scalzo, Ke Sheng* Medical Physics 2022 http://doi.org/10.1002/mp.15983

• Feasibility of a Novel Sparse Orthogonal Collimator–Based Preclinical Total Marrow Irradiation for Enhanced Dosimetric Conformality Amr M. H. Abdelhamid, Lu Jiang, Darren Zuro, An Liu, Srideshikan Sargur Madabushi, Hemendra Ghimire, Jeffrey Y. C. Wong, Simonetta Saldi, Christian Fulcheri, Claudio Zucchetti, Antonio Pierini, Ke Sheng, Cynthia Aristei and Susanta K. Hui Front. Oncol., 18 July 2022, https://doi.org/10.3389/fonc.2022.941814

• Reformulated McNamara RBE-weighted Beam Orientation Optimization for Intensity Modulated Proton Therapy, Pavitra Ramesh, Qihui Lyu, Wenbo Gu, Dan Ruan, and Ke Sheng, Med Phys. 2022 Apr;49(4):2136-2149. doi: 10.1002/mp.15552

• A Prospective Phase II Study of Automated Non-Coplanar VMAT for Recurrent Head and Neck Cancer:  Initial Report of Feasibility, Safety, and Patient Reported Outcomes Kaley Woods Ting Martin Ma, Kelsey Narahara, Zhouhuizi Shen, Eric Morris, Yu Gao, Kiri A. Cook, Ke Sheng, Amar U. Kishan, John V. Hegde, Carol Felix,  Vincent Basehart, Stephen Tenn, Michael Steinberg, Robert K. Chin MD, Minsong Cao Cancers 2022, 14(4), 939; https://doi.org/10.3390/cancers14040939

• Dosimetric Impact of Interfraction Prostate and Seminal Vesicle Volume Changes and Rotation: A Post-Hoc Analysis of a Phase III Randomized Trial of MRI-Guided versus CT-Guided Stereotactic Body Radiotherapy Ting Martin Ma, Minsong Cao, Jack Neylon, Maria Casado, Sahil Sharma, Ke Sheng, Daniel Low, Yingli Yang, Michael L. Steinberg, James Lamb, Amar U. Kishan, Radiotherapy and Oncology, Volume 167, February 2022, Pages 203-210  https://doi.org/10.1016/j.radonc.2021.12.037 

• To what extent can Plug-and-Play methods outperform neural networks alone in low-dose CT reconstruction, Qifan Xu, Qihui Lyu, Dan Ruan, Ke Sheng, ISBI 2022 https://arxiv.org/abs/2202.07173

2021

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• Voxel-wise prediction of recurrent brain GBM via proximity estimation coupled multi-dimensional SVM Yi Lao, Dan Ruan, April Vassantachart, Zhaoyang Fan, Jason C. Ye, Eric L. Chang, Robert Chin, Tania Kaprealian, Gabriel Zada, Mark S Shiroishi,  Ke Sheng, and Wensha Yang, International Journal of Radiation.Oncology.Biology.Physics, 2021 https://doi.org/10.1016/j.ijrobp.2021.12.153

• Bladder surface dose modeling in prostate cancer radiotherapy: an analysis of motion-induced variations and the cumulative dose across the treatment. Yi Lao, Minsong Cao, Yingli Yang, Amar U. Kishan1, Wensha Yang, Yalin Wang, and Ke Sheng, Med Phys.2021;48:8024–8036, DOI: 10.1002/mp.15326

• Novel technologies for Linac-based radiotherapy Sergey V. Kutsaev, Salime Boucher, Brahim Mustapha, Ke Sheng Proceedings Volume 11838, Hard X-Ray, Gamma-Ray, and Neutron Detector Physics XXIII; 118380U (2021) https://doi.org/10.1117/12.2595707

• Clinical assessment of geometric distortion for a 0.35T MR-guided radiotherapy system. Neylon J, Cook KA, Yang Y, Du D, Sheng K, Chin RK, Kishan AU, Lamb JM, Low DA, Cao M. J Appl Clin Med Phys. 2021 Jul 7. doi: 10.1002/acm2.13340. Online ahead of print. PMID: 34231963

• Fixed Beamline Optimization for Intensity Modulated Carbon-Ion Therapy, Pavitra Ramesh, Hengjie Liu, Wenbo Gu, and Ke Sheng IEEE Transactions on Radiation and Plasma Medical Sciences 2021 DOI:10.1109/TRPMS.2021.3092296

• Using Neural Networks to Extend Cropped Medical Images for Deformable Registration Among Images with Differing Scan Extents, Elizabeth M. McKenzie, Nuo Tong, Dan Ruan, Minsong Cao, Robert K. Chin, Ke Sheng, Medical Physics 2021 DOI: 10.1002/mp.15039 

• Magnetic Resonance Imaging-Guided Stereotactic Body Radiotherapy for Prostate Cancer (MIRAGE): A Phase III Randomized Trial, Ting Martin Ma, James M. Lamb, Maria Casado, Xiaoyan Wang, T. Vincent Basehart, Yingli Yang, Daniel Low, Ke Sheng, Nzhde Agazaryan, Nicholas G. Nickols, Minsong Cao, Michael L. Steinberg, Amar U. Kishan BMC Cancer 2021 DOI: 10.1186/s12885-021-08281-x

• Automated Non-Coplanar VMAT for Dose Escalation in Recurrent Head and Neck Cancer Patients,  Kaley Woods, Robert K. Chin, Kiri A. Cook, Ke Sheng, Amar U. Kishan, John V. Hegde, Stephen Tenn, Michael Steinberg, Minsong Cao, Cancers, 2021 DOI: 10.3390/cancers13081910

• Yi Lao, Victoria Yu, Anthony Pham, Theodore Wang, Jing Cui, Audrey Gallogly, Eric Chang, Zhaoyang Fan, Tania Kaprealian, Wensha Yang, Ke Sheng*, Quantitative characterization of tumor proximity to stem cell niches: implications on recurrence and survival in GBM patients, Int. J. Radiation Oncology.Biology.Physics 2021 In press DOI: https://doi.org/10.1016/j.ijrobp.2021.02.020

• Victoria Y. Yu, Dan Nguyen, Daniel O’Connor, Dan Ruan, Tania Kaprealian, Robert Chin, Ke Sheng*, Treating Glioblastoma Multiforme (GBM) with super hyperfractionated radiation therapy: Implication of temporal dose fractionation optimization including cancer stem cell dynamics,  PLOS ONE 2021 https://doi.org/10.1371/journal.pone.0245676

• DeepMC: A Deep Learning Method for Efficient Monte Carlo Beamlet Dose Calculation by Predictive Denoising in Magnetic Resonance-Guided Radiotherapy Ryan Neph, Qihui Lyu, Yangsibo Huang, You Ming Yang, Ke Sheng*, Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abca01

2020

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• Weak Magnetic Fields Enhance the Efficacy of Radiotherapy Advances in Radiation Oncology, Robert Sandstrom, Mark Bryan, Yue Liu, Robin S Elgart, Ke Sheng, Michael Steinberg, William McBride, Daniel Low, Kei Iwamoto, Advances in Radiation Oncology, 2020

• ROAD: ROtational direct Aperture optimization with a Decoupled ring-collimator for FLASH radiotherapy, Lyu, Qihui; Neph, Ryan; O'Connor, Daniel; Ruan, Dan; Boucher, Salime; Sheng, Ke*, Physics and Medicine in Biology, 2020, https://iopscience.iop.org/article/10.1088/1361-6560/abcbd0/meta

• Multi-task Edge-recalibrated Network for Male Pelvic Multi-Organ Segmentation on CT Images, Tong, Nuo; Gou, Shuiping; Chen, Shuzhe; Yao, Yao; Yang, Shuyuan; Cao, Minsong; Kishan, Amar; Sheng, Ke*, Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abcad9

• Automatic detection and segmentation of multiple brain metastases on magnetic resonance image using asymmetric UNet architecture,  Cao, Yufeng; Vassantachart, April; Ye, Jason; Yu, Cheng; Ruan, Dan; Sheng, Ke; Lao, Yi; Shen, Zhilei; Balik, Salim; Bian, Shelly; Zada, Gabriel; Shiu, Almon; Chang, Eric; Yang, Wensha Physics and Medicine in Biology, 2020, DOI: 10.1088/1361-6560/abca53

• Analysis of Geometric Performance and Dosimetric Impact of using Automatic Contour Segmentation for Radiotherapy Planning, Minsong Cao, Bradley Stiehl, Victoria Yu, Ke Sheng, Amar Kishan, Robert K. Chin, Yingli Yang, Dan Ruan, Frontiers in Oncology 2020 https://doi.org/10.3389/fonc.2020.01762

• Practical Safety Considerations for Integration of Magnetic Resonance Imaging in Radiation Therapy, Minsong Cao, Brad Stiehl, Victoria Yu, Ke Sheng, Amar Kishan, Robert Chin, Yingli Yang, Dan Ruan, Practical Radiation Oncology, 2020 https://doi.org/10.1016/j.prro.2020.07.008

• Fraction-Variant Beam Orientation Optimization for Intensity-Modulated Proton Therapy, Wenbo Gu, Daniel O’Connor, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2020 https://doi.org/10.1002/mp.14340

• Self-paced DenseNet with Boundary Constraint for Automated Multi-Organ Segmentation on Abdominal CT Images, Tong, Nuo; Gou, Shuiping; Niu, Tianye; Yang, Shuyuan; Sheng, Ke, Physics and Medicine in Biology 2020 65 135011 https://doi.org/10.1088/1361-6560/ab9b57

• Linear Energy Transfer Weighted Beam Orientation Optimization for Intensity-Modulated Proton Therapy, Wenbo Gu, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2020 https://doi.org/10.1002/mp.14329

• Iterative reconstruction of cone-beam breast CT using plug-and-play projected gradient descent Qihui Lyu; Tianye Niu; Dan Ruan; Ke Sheng  Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 113124J (16 March 2020); doi: 10.1117/12.2549787

• Deformable alignment of longitudinal postoperative brain GBM scans using deep learning Yi Lao; Victoria Yu; Eric Chang; Wensha Yang; Ke Sheng Proceedings Volume 11313, Medical Imaging 2020: Image Processing; 113130O (2020) https://doi.org/10.1117/12.2549129

• Quantifying vascular invasion in pancreatic cancer - a contrast CT based method for surgical resectability evaluation, Lao, Yi; David, John ; Fan, Zhaoyang; Bian, Shelly ; Shiu, Almon ; CHANG, ERIC; Sheng, Ke; Yang, Wensha; Tuli, Richard, Physics and Medicine in Biology, 2020 DOI: 10.1088/1361-6560/ab8106

• Artificial Intelligence in Radiotherapy: A Technological Review, Ke Sheng, Frontiers of Medicine, 2020 https://doi.org/10.1007/s11684-020-0761-1

• Self-Channel-and-Spatial-Attention Neural Network for Automated Multi-Organ Segmentation on Head and Neck CT Images, Tong, Nuo; Gou, Shuiping; Qi, Sharon; Yang, Shuyuan; Chin, Robert K.; Sheng, Ke, Physics and Medicine in Biology, 2020 accepted  https://iopscience.iop.org/article/10.1088/1361-6560/ab79c3

• A Novel Energy Layer Optimization Framework for Spot-Scanning Proton Arc Therapy, Wenbo Gu, Dan Ruan, Qihui Lyu, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics, accepted 2020 https://aapm.onlinelibrary.wiley.com/doi/pdf/10.1002/mp.14083

• Many-isocenter Optimization for Robotic Radiotherapy, Qihui Lyu, Ryan Neph, Victoria Yu, Ran Ruan, Salime Boucher, Ke Sheng, Phys. Med. Biol. 65 (2020) 045003 (14pp) https://iopscience.iop.org/article/10.1088/1361-6560/ab63b8

• Image domain multi-material decomposition using single energy CT, Yi Xue, Yangkang Jiang, Pengfei Yang, Lei Xu, Chen Luo, Xi Hu, Jing Wang, Xiuhua Xu, Ke Sheng, Tianye Niu, Physics and Medicine in Biology, accepted 2020, https://iopscience.iop.org/article/10.1088/1361-6560/ab7503

2019

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• Multimodality Image Registration in the Head-and-Neck using a Deep Learning Derived Synthetic CT as a Bridge, Elizabeth McKenzie, Anand Santhanam, Dan Ruan, Daniel O'Connor, Minsong Cao, and Ke Sheng Medical Physics, accepted 2019 https://doi.org/10.1002/mp.13976

• Technical Note: Robust individual Thermoluminescence dosimeter tracking using optical fingerprinting Daili Shang, Wenbo Gu, Angelia Landers, Kaley Woods, Victoria Yu, Ryan Neph, Stephen Tenn, and Ke Sheng, Medical Physics 2019 https://doi.org/10.1002/mp.13895

• Fully Automated Pancreas Segmentation with Two-Stage 3D Convolutional Neural Networks, Ningning Zhao, Nuo Tong, Dan Ruan, and Ke ShengMICCAI 2019, LNCS 11765, pp. 201–209, 2019 https://doi.org/10.1007/978-3-030-32245-8_23

• DeepMCDose: A Deep Learning Method for Efficient Monte Carlo Beamlet Dose Calculation by Predictive Denoising in MR-Guided Radiotherapy  Ryan Neph, Yangsibo Huang, Youming Yang, and Ke Sheng, AIRT 2019, LNCS 11850, pp. 137–145, 2019. https://doi.org/10.1007/978-3-030-32486-5_17

• Image-domain multimaterial decomposition for dual-energy computed tomography with nonconvex sparsity regularization, Qihui Lyu, Daniel O’Connor, Tianye Niu, Ke Sheng*J. Med. Imag. 6(4), 044004 (2019), doi: 10.1117/1.JMI.6.4.044004

• Noise Suppression in Image-domain Multi-material Decomposition for Dual-energy CTs Yangkang Jiang, Yi Xue, Qihui Lyu, Lei Xu, Chen Luo, Pengfei Yang, Chunlin Yang, Jing Wang, Xi Hu, Xiaoqun Zhang, Ke Sheng, Tianye Niu IEEE Trans Biomed Eng 2019 DOI: 10.1109/TBME.2019.2916907

• A Sparse Orthogonal Collimator for Small Animal Intensity Modulated Radiation Therapy Part II: Hardware Development and Commissioning Kaley Woods, Ryan Neph, Dan Nguyen, Ke Sheng  Medical Physics 2019 DOI:10.1002/mp.13870

• A Sparse Orthogonal Collimator for Small Animal Intensity Modulated Radiation Therapy Part I: Planning System Development and Commissioning, Kaley Woods, Dan Nguyen, Ryan Neph, Dan Ruan, Daniel O’Connor, Ke Sheng, Medical Physics 2019 DOI:10.1002/mp.13872

• Automated 4π Radiotherapy Treatment Planning with Evolving Knowledge-Base Angelia Landers, Daniel O’Connor, Dan Ruan and Ke Sheng, Medical Physics 2019 https://doi.org/10.1002/mp.13651

• Parallel Beamlet Dose Calculation via Beamlet Contexts in a Distributed Multi-GPU Framework, R. Neph, C. Ouyang, J. Neylon, Y. M. Yang, and K. Sheng, Medical Physics 2019 June

• Robust Beam Orientation Optimization for Intensity-Modulated Proton Therapy  Wenbo Gu, Ryan Neph, Dan Ruan, Wei Zou, Lei Dong, and Ke Sheng, Medical Physics 2019 June  DOI:10.1002/mp.13641

• Scatter correction of cone-beam CT using a deep residual convolution neural network (DRCNN)  Jiang, Yangkang; Yang, Chunlin; Yang, Pengfei; Hu, Xi; Luo, Chen; Xue, Yi; Xu, Lei; Hu, Xiuhua; Zhang, Luhan; Wang, Jing; Sheng, Ke; Niu, Tianye, Physics in Medicine and Biology, 2019 64 145003

• Shape Constrained Fully Convolutional DenseNet with Adversarial Training for Multi-organ Segmentation on Head and Neck CT and Low Field MR Images Nuo Tong, Shuiping Gou, Shuyuan Yang, Minsong Cao, and Ke Sheng Medical Physics 2019 46 (6), June 2019 0094-2405 https://doi.org/10.1002/mp.13553

• Iterative reconstruction for low dose CT using Plug-and-Play alternating direction method of multipliers (ADMM) framework Qihui Lyu, Dan Ruan, John Hoffman, Ryan Neph, Michael McNitt-Gray, Ke Sheng Proceedings Volume 10949, Medical Imaging 2019: Image Processing; 1094906 (2019) https://doi.org/10.1117/12.2512484

• Image-domain multi-material decomposition for dual-energy CT with non-convex sparsity regularization Qihui Lyu, Daniel O'Connor, Tianye Niu, Ke Sheng, Proceedings Volume 10949, Medical Imaging 2019: Image Processing; 1094903 (2019) https://doi.org/10.1117/12.2508037

• Single-Arc VMAT optimization for Dual-Layer MLC, Qihui Lyu, Ryan Neph, Victoria Y Yu, Dan Ruan, Ke Sheng, Physics and Medicine in Biology, 2019 64 095028
• Motion Compensated Dynamic MRI Reconstruction with Local Affine Optical Flow Estimation , Ningning Zhao, Daniel O’Connor, Adrian Basarab, Dan Ruan, Ke Sheng, IEEE Transaction on Biomedical Engineering 2019 DOI:10.1109/TBME.2019.2900037

2018

• Robust Optimization for Intensity-Modulated Proton Therapy with Soft Spot Sensitivity Regularization, Wenbo Gu , Dan Ruan , Daniel O'Connor , Wei Zou , Lei Dong , Min-yu Tsai , Xun Jia , Ke Sheng, Medical Physics  2019 46 (3), 1408-1425 https://doi.org/10.1002/mp.13344

• Performance Comparison of Knowledge-Based Dose Prediction Techniques Based on Limited Patient Data, Angelia Landers, Ryan Neph, Fabien Scalzo, Dan Ruan, Ke Sheng, TCRT 2018

• Fully Automatic Multi-Organ Segmentation for Head and Neck Cancer Radiotherapy Using Shape Representation Model Constrained Fully Convolutional Neural Networks, Nuo Tong, Shuiping Gou, Shuyuan Yang, Dan Ruan and Ke Sheng Medical Physics 2018 45(10) 0094-2405 https://doi.org/10.1002/mp.13147

• A novel optimization framework for VMAT with dynamic gantry couch rotation, Lyu, Qihui; Yu, Victoria; Ruan, Dan; Neph, Ryan; O'Connor, Daniel; Sheng, Ke,  2018 Phys. Med. Biol. 63 125013

• Respiratory motion-resolved, self-gated 4D-MRI using rotating Cartesian k-space (ROCK): Initial clinical experience on an MRI-guided radiotherapy system Han F, Zhou Z, Du D, Gao Y, Rashid S, Cao M, Shaverdian N, Hegde JV, Steinberg M, Lee P, Raldow A, Low DA, Sheng K, Yang Y, Hu P.,Radiother Oncol. 2018 May 9. pii: S0167-8140(18)30221-4. doi: 10.1016/j.radonc.2018.04.029.

• A career path for pure academic medical physicists in radiation oncology should be established, Ke Sheng, Todd Pawlicki, Jing Cai, Medical Physics 2018  https://doi.org/10.1002/mp.12921

• Response to “in regard to “Tran A, Zhang J, Woods K, Yu V, Nguyen D, Gustafson G, Rosen L, Sheng K. Treatment planning comparison of IMPT, VMAT and 4π radiotherapy for prostate cases ”” Ke Sheng, Radiation Oncology 2018 13:66 https://doi.org/10.1186/s13014-018-1010-5

• VMAT optimization with dynamic collimator rotation , Qihui Lyu, Daniel O'Connor, Dan Ruan, Victoria Yu, Dan Nguyen, Ke Sheng, Medical Physics, 2018 https://doi.org/10.1002/mp.12915

• Technical note: Iterative Megavoltage CT (MVCT) Reconstruction using Block-Matching 3D-Transform (BM3D) Regularization , Qihui Lyu , Chunlin Yang , Hao Gao , Yi Xue , Daniel O'Connor , Tianye Niu , Ke Sheng*, Medical Physics 2018 https://doi.org/10.1002/mp.12916

• 4pi plan optimization for cortical-sparing brain radiotherapy Slava Murzin, Kaley Woods, Roshan Karunamuni, Tyler Seibert, Vitali Moiseenko, Daniel Simpson, Kathryn Tringale, Ke Sheng, Jona Hattangadi-Gluth, Radiotherapy and Oncology, Volume 127, Issue 1, April 2018, Pages 128-135  DOI: https://doi.org/10.1016/j.radonc.2018.02.011

• Cochlea-Sparing Acoustic Neuroma Treatment with 4pi Radiotherapy   Kaley Woods, Percy Lee, Tania Kaprealian, Isaac Yang, Ke Sheng, Advances in Radiation Oncology, 2018 In Press DOI: https://doi.org/10.1016/j.adro.2018.01.004

• Coupling reconstruction and motion estimation for dynamic MRI through optical flow constraint Ningning Zhao, Daniel O'Connor, Wenbo Gu, Dan Ruan, Adrian Basarab, and Ke Sheng Proceedings Volume 10574, Medical Imaging 2018: Image Processing; 1057429 (2018); doi: 10.1117/12.2293878
• Fraction-variant beam orientation optimization for non-coplanar IMRT  Daniel O'Connor, Victoria Yu, Dan Nguyen, Dan Ruan, Ke Sheng*,  Physics in Medicine and Biology, In Press 2018 doi: 10.1088/1361-6560/aaa94f.
• Integrated Beam Orientation and Scanning-Spot Optimization in Intensity Modulated Proton Therapy for Brain and Unilateral Head and Neck Tumors, Wenbo Gu, Daniel O'Connor, Dan Nguyen, Victoria Yu, Dan Ruan, Lei Dong, Ke Sheng*, Medical Physics,  45 (4) 2018 DOI: 10.1002/mp.12788 
• A Prospective 4pi Radiotherapy Clinical Study in Recurrent High Grade Glioma Patients,Victoria Yu, Angelia Tran, Kaley Woods, Minsong Cao, Robert Chin, Ke Sheng*, Tania Karealian*, Int. Journal of Radiation Oncology, Biology, Physics, Volume 101, Issue 1, 1 May 2018, Pages 144-151, https://doi.org/10.1016/j.ijrobp.2018.01.048

2017

• Radioresistance of the breast tumor is highly correlated to its level of cancer stem cell and its clinical implication for breast irradiation , X. Sharon Qi, Frank Pajonk, Susan McCloskey, Daniel A. Low, Patrick Kupelian, Michael Steinberg, Ke Sheng, Radiotherapy and Oncology, Volume 124, Issue 3, September 2017, Pages 455-461, https://doi.org/10.1016/j.radonc.2017.08.019
• Deterministic Direct Aperture Optimization Using Multiphase Piecewise Constant Segmentation, Dan Nguyen , Daniel O'Connor , Dan Ruan , Ke Sheng, Medical Physics 2017 44(10) DOI: 10.1002/mp.12529
• Multi-Institutional MicroCT Image Comparison of Image-Guided Small Animal Irradiators, Chris D. Johnstone, Patricia Lindsay, Edward E. Graves, Eugene Wong, Jessica R. Perez, Yannick Poirier, Youssef Ben-Bouchta, Thilakshan Kanesalingam, Haijian Chen, Ashley E. Rubinstein,  Ke Sheng, Magdalena Bazalova-Carter Phys. Med. Biol. 62 (2017) 5760–5776
• Predicting Liver SBRT Eligibility and Plan Quality for VMAT and 4π Plans, Angelia Tran; Kaley Woods; Dan Nguyen; Victoria Yu; Tianye Niu; Minsong Cao; Percy Lee; Ke Sheng* Radiation Oncology 201712:70 DOI: 10.1186/s13014-017-0806-z
• Treatment planning comparison of IMPT, VMAT and 4pi radiotherapy for prostate cases , Angelia Tran, Jingjing Zhang, Kaley Woods, Victoria Yu, Dan Nguyen, Gary Gustafson, Lane Rosen, and Ke Sheng* Radiation Oncology (2017) 12:10 DOI 10.1186/s13014-016-0761-0
• Feasibility evaluation of diffusion-weighted imaging using an integrated MRI-radiotherapy system for response assessment to neoadjuvant therapy in rectal cancer , Narek Shaverdian, Yingli Yang, Peng Hu, Steve Hart, Ke Sheng, James Lamb, Minsong Cao, Nzhde Agazaryan, David Thomas, Michael Steinberg, Daniel Low, Percy Lee. Br J Radiol. 2017 Mar;90(1071):20160739. doi: 10.1259/bjr.20160739. 
• Respiratory motion resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK) Fei Han, Ziwu Zhou, Minsong Cao, Yingli Yang, Ke Sheng, Peng Hu, Med Phys. 2017 Jan 30. doi: 10.1002/mp.12139. 

2016

• A Treatment Planning Comparison between Modulated Tri-Cobalt-60 Teletherapy and LINAC-Based Stereotactic Body Radiotherapy for Central Early-Stage Non-Small Cell Lung Cancer Catherine Merna, Jean-Claude M. Rwigema, Minsong Cao, Pin-Chieh Wang, Amar U. Kishan, Argin Michailian, James Lamb, Ke Sheng, Nzhde Agazaryan, Daniel A. Low, Patrick Kupelian, Michael L. Steinberg, Percy Lee 2016 Jan 2. pii: S0958-3947(15)00108-9. doi: 10.1016/j.meddos.2015.09.002.
• The Development and Verification of a Highly Accurate Collision Prediction Model for Automated Non-coplanar Plan Delivery , Victoria Y. Yu, Angelia Tran, Dan Nguyen, Minsong Cao, Dan Ruan, Daniel A. Low and Ke Sheng*, Medical Physics 42, 6457 (2015); doi: 10.1118/1.4932631
• Iterative CT shading correction with no prior information Pengwei Wu, Xiaonan Sun, Hongjie Hu, Tingyu Mao, Wei Zhao, Ke Sheng, Alice Cheung, Tianye Niu, Physics in Medicine and Biology 2015 Nov 7;60(21):8437-55. doi: 10.1088/0031-9155/60/21/84372015
• UTE-MRI-based Treatment Simulation and Patient Setup for Radiation Therapy of Brain Cancer , Yingli Yang, Minsong Cao, Tania Kaprealian, Ke Sheng Yu Gao, Fei Han, Caitlin Gomez, Anand Santhanam, Stephen Tenn, Daniel A Low, Peng Hu, Med. Phys. 43, 262 (2016); http://dx.doi.org/10.1118/1.4938266
• Viability of Non-Coplanar VMAT for Liver SBRT as Compared to Coplanar VMAT and Beam Orientation Optimized 4 IMRT Advances in Radiation Oncology Kaley Woods, Dan Nguyen, Angelia Tran, Victoria Y. Yu, Minsong Cao, Tianye Niu, Percy Lee, Ke Sheng*, Volume 1, Issue 1, January-March 2016, Pages 67-75 doi:10.1016/j.adro.2015.12.004
• A Novel Software and Conceptual Design of the Hardware Platform for Intensity Modulated Radiation Therapy , Dan Nguyen, Dan Ruan, Daniel O'Connor, Kaley Woods, Daniel A. Low, Salime Boucher, and Ke Sheng* Medical Physics 43, 917 (2016); doi: 10.1118/1.4940353
• Systematic feasibility analysis of a quantitative elasticity estimation for breast anatomy using supine/prone patient postures Katelyn Hasse*, John P Neylon , Ke Sheng, Anand Santhanam, Medical Physics 43, 1299 (2016); doi: 10.1118/1.4941745 82.
• Non-local means denoising of SG-KS-4D-MRI using block matching 3D: Implications for pancreatic tumor registration and segmentation , Jun Jin, Elizabeth Boehnke-McKenzie, Zhaoyan Fan, Richard Tuli, Ke Sheng, Howard Sandler Shuiping Gou, and Wensha Yang*, International Journal of Radiation Oncology, Biology, Physics Volume 95, Issue 3, 1 July 2016, Pages 1058-1066 http://dx.doi.org/10.1016/j.ijrobp.2016.02.006
• Non-local means denoising of SG-KS-4D-MRI using block matching 3D: Implications for pancreatic tumor registration and segmentation , Jun Jin, Elizabeth Boehnke-McKenzie, Zhaoyan Fan, Richard Tuli, Ke Sheng, Howard Sandler Shuiping Gou, and Wensha Yang*, International Journal of Radiation Oncology, Biology, Physics Volume 95, Issue 3, 1 July 2016, Pages 1058-1066 http://dx.doi.org/10.1016/j.ijrobp.2016.02.006
• Longitudinal Diffusion MRI for Treatment Response Assessment: Preliminary Experience using an MRI-Guided tri-Cobalt 60 Radiotherapy System , Yingli Yang, Minsong Cao, Ke Sheng, Yu Gao, Allen Chen, Mitchell Kamrava, Percy Lee, Nzhde Agazaryan, James Lamb, David Thomas, Daniel Low, Peng Hu, Medical Physics 43, 1369 (2016); doi: 10.1118/1.4942381
• Modeling and simulation of tumor-influenced high resolution real-time physics-based breast models for model-guided robotic interventions , John Neylon ; Katelyn Hasse ; Ke Sheng ; Anand P. Santhanam Proc. SPIE 9786, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, 97860X (March 18, 2016); doi:10.1117/12.2217028
• Feasibility of automated 3D MRI pancreas segmentation Shuiping Gou, Percy Lee, Peng Hu, Jean-Claude Rwigema, Ke Sheng* Advances in Radiation Oncology 2016 doi: 10.1016/j.adro.2016.05.002
• A Comprehensive Formulation for Volumetric Modulated Arc Therapy Planning Dan Nguyen, Qihui Lyu, Dan Ruan, Daniel O'Connor, Daniel A. Low, Ke Sheng* Medical Physics 43, 4263 (2016); doi: 10.1118/1.4953832
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